Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation

Fragile X syndrome (FXS) is the most frequent inherited cause of intellectual disability and the best-studied monogenic cause of autism. FXS results from the functional absence of the fragile X mental retardation protein (FMRP) leading to abnormal pruning and consequently to synaptic communication d...

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Udgivet i:Nat Commun
Main Authors: Khayachi, Anouar, Gwizdek, Carole, Poupon, Gwénola, Alcor, Damien, Chafai, Magda, Cassé, Frédéric, Maurin, Thomas, Prieto, Marta, Folci, Alessandra, De Graeve, Fabienne, Castagnola, Sara, Gautier, Romain, Schorova, Lenka, Loriol, Céline, Pronot, Marie, Besse, Florence, Brau, Frédéric, Deval, Emmanuel, Bardoni, Barbara, Martin, Stéphane
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823917/
https://ncbi.nlm.nih.gov/pubmed/29472612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03222-y
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