Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter

The active transport of glycolytic pyruvate across the inner mitochondrial membrane is thought to involve two mitochondrial pyruvate carrier subunits, MPC1 and MPC2, assembled as a 150 kDa heterotypic oligomer. Here, the recombinant production of human MPC through a co-expression strategy is first d...

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Publicado no:Sci Rep
Main Authors: Nagampalli, Raghavendra Sashi Krishna, Quesñay, José Edwin Neciosup, Adamoski, Douglas, Islam, Zeyaul, Birch, James, Sebinelli, Heitor Gobbi, Girard, Richard Marcel Bruno Moreira, Ascenção, Carolline Fernanda Rodrigues, Fala, Angela Maria, Pauletti, Bianca Alves, Consonni, Sílvio Roberto, de Oliveira, Juliana Ferreira, Silva, Amanda Cristina Teixeira, Franchini, Kleber Gomes, Leme, Adriana Franco Paes, Silber, Ariel Mariano, Ciancaglini, Pietro, Moraes, Isabel, Dias, Sandra Martha Gomes, Ambrosio, Andre Luis Berteli
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823908/
https://ncbi.nlm.nih.gov/pubmed/29472561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21740-z
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