Teneligliptin enhances the beneficial effects of GLP-1 in endothelial cells exposed to hyperglycemic conditions

High-glucose-induced oxidative stress contributes to cardiovascular endothelial damage in diabetes. Glucagon-like peptide 1 (GLP-1) is beneficial to endothelial cells, but its effects are diminished when cells are continuously exposed to high glucose. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: De Nigris, Valeria, Prattichizzo, Francesco, Mancuso, Elettra, Spiga, Rosangela, Pujadas, Gemma, Ceriello, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823668/
https://ncbi.nlm.nih.gov/pubmed/29507662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22849
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