High GSTP1 inhibits cell proliferation by reducing Akt phosphorylation and is associated with a better prognosis in hepatocellular carcinoma

Glutathione S-transferase (GST) family members promote carcinogenesis and cancer progression. We assessed GST pi 1 (GSTP1) mRNA and protein levels in hepatocellular carcinoma (HCC) using genome databases and tissue microarray (TMA) technology. We found that in cancerous tissues, GSTP1 mRNA was down-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Xiaojia, Tan, Ning, Liao, Hongtao, Pan, Guangdong, Xu, Qing, Zhu, Rong, Zou, Liping, He, Songqing, Zhu, Hongguang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823662/
https://ncbi.nlm.nih.gov/pubmed/29507666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23420
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