Copper/MYC/CTR1 interplay: a dangerous relationship in hepatocellular carcinoma

Free serum copper correlates with tumor incidence and progression of human cancers, including hepatocellular carcinoma (HCC). Copper extracellular uptake is provided by the transporter CTR1, whose expression is regulated to avoid excessive intracellular copper entry. Inadequate copper serum concentr...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Porcu, Cristiana, Antonucci, Laura, Barbaro, Barbara, Illi, Barbara, Nasi, Sergio, Martini, Maurizio, Licata, Anna, Miele, Luca, Grieco, Antonio, Balsano, Clara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823635/
https://ncbi.nlm.nih.gov/pubmed/29507693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24282
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