Differentially expressed microRNAs in lung adenocarcinoma invert effects of copy number aberrations of prognostic genes

In many cancers, significantly down- or upregulated genes are found within chromosomal regions with DNA copy number alteration opposite to the expression changes. Generally, this paradox has been overlooked as noise, but can potentially be a consequence of interference of epigenetic regulatory mecha...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Tokar, Tomas, Pastrello, Chiara, Ramnarine, Varune R., Zhu, Chang-Qi, Craddock, Kenneth J., Pikor, Larrisa A., Vucic, Emily A., Vary, Simon, Shepherd, Frances A., Tsao, Ming-Sound, Lam, Wan L., Jurisica, Igor
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823624/
https://ncbi.nlm.nih.gov/pubmed/29507679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24070
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