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A NOVEL AND EFFICIENT ALGORITHM FOR DE NOVO DISCOVERY OF MUTATED DRIVER PATHWAYS IN CANCER

Next-generation sequencing studies on cancer somatic mutations have discovered that driver mutations tend to appear in most tumor samples, but they barely overlap in any single tumor sample, presumably because a single driver mutation can perturb the whole pathway. Based on the corresponding new con...

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Detalhes bibliográficos
Publicado no:Ann Appl Stat
Main Authors: Liu, Binghui, Wu, Chong, Shen, Xiaotong, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823541/
https://ncbi.nlm.nih.gov/pubmed/29479394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/17-AOAS1042
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