Focused Ultrasound-Facilitated Brain Drug Delivery Using Optimized Nanodroplets: Vaporization Efficiency Dictates Large Molecular Delivery

Focused ultrasound with nanodroplets could facilitate localized drug delivery after vaporization with potentially improved in vivo stability, drug payload, and minimal interference outside of the focal zone compared with microbubbles. While the feasibility of blood-brain barrier (BBB) opening using...

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Veröffentlicht in:Phys Med Biol
Hauptverfasser: Wu, Shih-Ying, Fix, Samantha M., Arena, Christopher, Chen, Cherry C., Zheng, Wenlan, Olumolade, Oluyemi O., Papadopoulou, Virginie, Novell, Anthony, Dayton, Paul A., Konofagou, Elisa E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823501/
https://ncbi.nlm.nih.gov/pubmed/29260735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1361-6560/aaa30d
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