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Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation

Pericentrin is a conserved centrosomal protein whose dysfunction has been linked to several human diseases. It has been implicated in many aspects of centrosome and cilia function, but its precise role is unclear. Here, we examine Drosophila Pericentrin-like-protein (PLP) function in vivo in tissues...

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Publicado en:PLoS Genet
Autores principales: Roque, Helio, Saurya, Saroj, Pratt, Metta B., Johnson, Errin, Raff, Jordan W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823460/
https://ncbi.nlm.nih.gov/pubmed/29425198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007198
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