The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is the sixth most frequent cancer worldwide. The pregnane X receptor (PXR) is a nuclear receptor regulating several target genes associated with cancer malignancy. We here demonstrated a significant effect of PXR on HNSCC cell growth, as evidenced in PXR...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Rigalli, Juan Pablo, Reichel, Matthias, Reuter, Tasmin, Tocchetti, Guillermo Nicolás, Dyckhoff, Gerhard, Herold-Mende, Christel, Theile, Dirk, Weiss, Johanna
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823449/
https://ncbi.nlm.nih.gov/pubmed/29470550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193242
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