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A "late-but-fitter revertant cell" explains the high frequency of revertant mosaicism in epidermolysis bullosa

Revertant mosaicism, or “natural gene therapy”, is the phenomenon in which germline mutations are corrected by somatic events. In recent years, revertant mosaicism has been identified in all major types of epidermolysis bullosa, the group of heritable blistering disorders caused by mutations in the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van den Akker, Peter C., Pasmooij, Anna M. G., Joenje, Hans, Hofstra, Robert M. W., te Meerman, Gerard J., Jonkman, Marcel F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823395/
https://ncbi.nlm.nih.gov/pubmed/29470523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192994
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