Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism

Venous thromboembolism (VTE) is common in patients with brain tumors, and underlying mechanisms are unclear. We hypothesized that podoplanin, a sialomucin-like glycoprotein, increases the risk of VTE in primary brain tumors via its ability to induce platelet aggregation. Immunohistochemical staining...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Riedl, Julia, Preusser, Matthias, Nazari, Pegah Mir Seyed, Posch, Florian, Panzer, Simon, Marosi, Christine, Birner, Peter, Thaler, Johannes, Brostjan, Christine, Lötsch, Daniela, Berger, Walter, Hainfellner, Johannes A., Pabinger, Ingrid, Ay, Cihan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823234/
https://ncbi.nlm.nih.gov/pubmed/28073783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-720714
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