Loss of microRNA-22 prevents high-fat diet induced dyslipidemia and increases energy expenditure without affecting cardiac hypertrophy

Obesity is associated with development of diverse diseases, including cardiovascular diseases and dyslipidemia. MiRNA-22 (miR-22) is a critical regulator of cardiac function and targets genes involved in metabolic processes. Previously, we generated miR-22 null mice and we showed that loss of miR-22...

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Gepubliceerd in:Clin Sci (Lond)
Hoofdauteurs: Diniz, Gabriela Placoná, Huang, Zhan-Peng, Liu, Jianming, Chen, Jinghai, Ding, Jian, Fonseca, Renata Inzinna, Barreto-Chaves, Maria Luiza, Donato, Jose, Hu, Xiaoyun, Wang, Da-Zhi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822437/
https://ncbi.nlm.nih.gov/pubmed/29101298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20171368
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