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Tumor initiating cells induce Cxcr4-mediated infiltration of pro-tumoral macrophages into the brain

It is now clear that microglia and macrophages are present in brain tumors, but whether or how they affect initiation and development of tumors is not known. Exploiting the advantages of the zebrafish (Danio rerio) model, we showed that macrophages and microglia respond immediately upon oncogene act...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Chia, Kelda, Mazzolini, Julie, Mione, Marina, Sieger, Dirk
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821457/
https://ncbi.nlm.nih.gov/pubmed/29465400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31918
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