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Autophagy and mitophagy in hepatocarcinogenesis

Autophagy is required for benign hepatic tumors to progress into malignant hepatocellular carcinoma. In our recent studies, we found that autophagy, or more specifically mitophagy, was required to suppress TP53 and induce the expression of the transcription factor NANOG to maintain hepatic cancer st...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Oncol
Main Authors: Liu, Kai, Lee, Jiyoung, Ou, Jing-Hsiung James
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821411/
https://ncbi.nlm.nih.gov/pubmed/29487894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1405142
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