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Autophagy and mitophagy in hepatocarcinogenesis

Autophagy is required for benign hepatic tumors to progress into malignant hepatocellular carcinoma. In our recent studies, we found that autophagy, or more specifically mitophagy, was required to suppress TP53 and induce the expression of the transcription factor NANOG to maintain hepatic cancer st...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Liu, Kai, Lee, Jiyoung, Ou, Jing-Hsiung James
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821411/
https://ncbi.nlm.nih.gov/pubmed/29487894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1405142
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