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Genetic compensation triggered by actin mutation prevents the muscle damage caused by loss of actin protein

The lack of a mutant phenotype in homozygous mutant individuals’ due to compensatory gene expression triggered upstream of protein function has been identified as genetic compensation. Whilst this intriguing process has been recognized in zebrafish, the presence of homozygous loss of function mutati...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Sztal, Tamar E., McKaige, Emily A., Williams, Caitlin, Ruparelia, Avnika A., Bryson-Richardson, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821405/
https://ncbi.nlm.nih.gov/pubmed/29420541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007212
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