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Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topology

Substantial evidence has accumulated linking epigenome change to alterations in stem cell function during postnatal development and aging. Yet much remains to be learned about causal relationships, and large gaps remain in our understanding of epigenome-transcriptome interactions. Here we investigat...

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Publicado en:PLoS One
Autores principales: Howard, Bruce H., Hirai, Tazuko H., Russanova, Valya R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821309/
https://ncbi.nlm.nih.gov/pubmed/29466355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191033
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