Associations of high-dose melphalan pharmacokinetics and outcomes in the setting of a randomized cryotherapy trial

High dose melphalan followed by autologous stem cell transplantation remains standard of care for eligible patients with multiple myeloma, but disease response and toxicity, including severe mucositis, varies among patients. Our randomized trial investigated duration of cryotherapy (2 and 6 hours) f...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Cho, Yu Kyoung, Sborov, Douglas W., Lamprecht, Misty, Li, Junan, Wang, Jiang, Hade, Erinn M., Gao, Yue, Tackett, Karen, Williams, Nita, Benson, Don M., Efebera, Yvonne A., Rosko, Ashley E., Devine, Steven M., Poi, Ming, Hofmeister, Craig C., Phelps, Mitch A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821248/
https://ncbi.nlm.nih.gov/pubmed/28160288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.644
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