Host DNA released by NETosis promotes rhinovirus-induced type 2 allergic asthma exacerbation

Respiratory viral infections represent the most common cause of allergic asthma exacerbations. Amplification of type 2 immune response is strongly implicated in asthma exacerbation, but how virus infection boosts type 2 responses is poorly understood. We report a significant correlation between rele...

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Udgivet i:Nat Med
Main Authors: Toussaint, Marie, Jackson, David J, Swieboda, Dawid, Guedán, Anabel, Tsourouktsoglou, Theodora-Dorita, Ching, Yee Man, Radermecker, Coraline, Makrinioti, Heidi, Aniscenko, Julia, Edwards, Michael R, Solari, Roberto, Farnir, Frédéric, Papayannopoulos, Venizelos, Bureau, Fabrice, Marichal, Thomas, Johnston, Sebastian L
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821220/
https://ncbi.nlm.nih.gov/pubmed/28459437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4332
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