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Renin-angiotensin-aldosterone system activation in long-standing type 1 diabetes

BACKGROUND. In type 1 diabetes (T1D), adjuvant treatment with inhibitors of the renin-angiotensin-aldosterone system (RAAS), which dilate the efferent arteriole, is associated with prevention of progressive albuminuria and renal dysfunction. Uncertainty still exists as to why some individuals with l...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lovshin, Julie A., Boulet, Geneviève, Lytvyn, Yuliya, Lovblom, Leif E., Bjornstad, Petter, Farooqi, Mohammed A., Lai, Vesta, Cham, Leslie, Tse, Josephine, Orszag, Andrej, Scarr, Daniel, Weisman, Alanna, Keenan, Hillary A., Brent, Michael H., Paul, Narinder, Bril, Vera, Perkins, Bruce A., Cherney, David Z.I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821172/
https://ncbi.nlm.nih.gov/pubmed/29321380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96968
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