Quantifying MHC Dextramer-induced NFAT activation in antigen-specific T cells as a functional response parameter

MHC-multimers are reagents used for the detection and enumeration of antigen-specific T cells (ASTs). These reagents exploit the mechanism by which T cell receptors (TCR) on cytotoxic CD8 T cells recognize specific antigens in the context of a major histocompatibility complex (MHC) molecule during a...

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Udgivet i:Methods
Main Authors: Maguire, Orla, Chen, George L., Hahn, Theresa E., Brix, Liselotte, McCarthy, Philip L., Wallace, Paul K., Minderman, Hans
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821144/
https://ncbi.nlm.nih.gov/pubmed/27327144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.06.014
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