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MicroRNA-21-5p mediates TGF-β-regulated fibrogenic activation of spinal fibroblasts and the formation of fibrotic scars after spinal cord injury

Little regeneration of transected axons occurs after the damage caused by traumatic spinal cord injury (SCI), and unidirectional and irreversible fibrotic scars are thought to be the main chemical and physical obstacle for axonal regrowth in SCI pathology. We previously demonstrated that microRNA (m...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Biol Sci
Main Authors: Wang, Wenzhao, Liu, Ronghan, Su, Yanlin, Li, Hongfei, Xie, Wei, Ning, Bin
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821039/
https://ncbi.nlm.nih.gov/pubmed/29483836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.24074
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