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Immunoproteasome Subunits Are Required for CD8(+) T Cell Function and Host Resistance to Brucella abortus Infection in Mice
The immunoproteasome is a specific proteasome isoform composed of three subunits, termed β1i, β2i, and β5i. Its proteolytic activity enhances the quantity and quality of peptides to be presented by major histocompatibility complex class I (MHC-I) molecules to CD8(+) T cells. However, the role of the...
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| Publicado no: | Infect Immun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5820958/ https://ncbi.nlm.nih.gov/pubmed/29263103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00615-17 |
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