Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial

IMPORTANCE: Tumor-treating fields (TTFields) is an antimitotic treatment modality that interferes with glioblastoma cell division and organelle assembly by delivering low-intensity alternating electric fields to the tumor. OBJECTIVE: To investigate whether TTFields improves progression-free and over...

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Detalhes bibliográficos
Publicado no:JAMA
Principais autores: Stupp, Roger, Taillibert, Sophie, Kanner, Andrew, Read, William, Steinberg, David M., Lhermitte, Benoit, Toms, Steven, Idbaih, Ahmed, Ahluwalia, Manmeet S., Fink, Karen, Di Meco, Francesco, Lieberman, Frank, Zhu, Jay-Jiguang, Stragliotto, Giuseppe, Tran, David D., Brem, Steven, Hottinger, Andreas F., Kirson, Eilon D., Lavy-Shahaf, Gitit, Weinberg, Uri, Kim, Chae-Yong, Paek, Sun-Ha, Nicholas, Garth, Bruna, Jordi, Hirte, Hal, Weller, Michael, Palti, Yoram, Hegi, Monika E., Ram, Zvi
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820703/
https://ncbi.nlm.nih.gov/pubmed/29260225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.18718
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