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Toward an integrated map of genetic interactions in cancer cells

Cancer genomes often harbor hundreds of molecular aberrations. Such genetic variants can be drivers or passengers of tumorigenesis and create vulnerabilities for potential therapeutic exploitation. To identify genotype‐dependent vulnerabilities, forward genetic screens in different genetic backgroun...

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Dades bibliogràfiques
Publicat a:Mol Syst Biol
Autors principals: Rauscher, Benedikt, Heigwer, Florian, Henkel, Luisa, Hielscher, Thomas, Voloshanenko, Oksana, Boutros, Michael
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820685/
https://ncbi.nlm.nih.gov/pubmed/29467179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177656
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