Persistent histone modifications at the BDNF promoter following extinction of nicotine-seeking in rats

Drugs of addiction lead to a wide range of epigenetic changes at the promoter regions of genes directly implicated in learning and memory processes. We have previously shown that the histone deactylase inhibitor, sodium butyrate (NaB), accelerates the extinction of nicotine-seeking and provides resi...

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Udgivet i:Genes Brain Behav
Main Authors: Castino, Matthew R., Baker-Andresen, Danay, Ratnu, Vikram S., Shevchenko, Galina, Morris, Kevin V., Bredy, Timothy W., Youngson, Neil A., Clemens, Kelly J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820208/
https://ncbi.nlm.nih.gov/pubmed/28857504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12421
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