Contrasting effects of individual versus combined estrogen and progestogen regimens as working memory load increases in middle-aged ovariectomized rats: one plus one does not equal two

The majority of estrogen-based hormone therapies are administered in combination with a progestogen, such as Levonorgestrel (Levo). Individually, the estrogen 17β-estradiol (E2) and Levo can improve cognition in preclinical models. However, although these hormones are often given together clinically...

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Pubblicato in:Neurobiol Aging
Autori principali: Prakapenka, Alesia V, Hiroi, Ryoko, Quihuis, Alicia M, Carson, Catie, Patel, Shruti, Berns-Leone, Claire, Fox, Carly, Sirianni, Rachael W., Bimonte-Nelson, Heather A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820186/
https://ncbi.nlm.nih.gov/pubmed/29316527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.11.015
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