Macrophage subpopulations and their impact on chronic allograft rejection versus graft acceptance in a mouse heart transplant model

Macrophages infiltrating the allografts are heterogeneous, consisting of pro-inflammatory (M1 cells) as well as anti-inflammatory and fibrogenic phenotypes (M2 cells); they affect transplant outcomes via diverse mechanisms. Herein, we found that macrophage polarization into M1 and M2 subsets was cri...

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Bibliografiske detaljer
Udgivet i:Am J Transplant
Main Authors: Zhao, Yue, Chen, Song, Lan, Peixiang, Wu, Chenglin, Dou, Yaling, Xiao, Xiang, Zhang, Zhiqiang, Minze, Laurie, He, Xiaoshun, Chen, Wenhao, Li, Xian C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820161/
https://ncbi.nlm.nih.gov/pubmed/29044999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14543
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