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iTRAQ Quantitative Proteomic Profiling and MALDI-MSI of Colon Cancer Spheroids Treated with Combination Chemotherapies in a 3D Printed Fluidic Device

For a patient with metastatic colorectal cancer there are limited clinical op-tions aside from chemotherapy. Unfortunately, the development of new chemot-herapeutics is a long and costly process. New methods are needed to identify promising drug candidates earlier in the drug development process. Mo...

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Detalles Bibliográficos
Publicado en:Anal Chem
Main Authors: LaBonia, Gabriel J., Ludwig, Katelyn R., Mousseau, C. Bruce, Hummon, Amanda B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820028/
https://ncbi.nlm.nih.gov/pubmed/29227110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04969
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