Cell-free synthesis of functional antibody fragments to provide a structural basis for antibody–antigen interaction

Growing numbers of therapeutic antibodies offer excellent treatment strategies for many diseases. Elucidation of the interaction between a potential therapeutic antibody and its target protein by structural analysis reveals the mechanism of action and offers useful information for developing rationa...

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Veröffentlicht in:PLoS One
Hauptverfasser: Matsuda, Takayoshi, Ito, Takuhiro, Takemoto, Chie, Katsura, Kazushige, Ikeda, Mariko, Wakiyama, Motoaki, Kukimoto-Niino, Mutsuko, Yokoyama, Shigeyuki, Kurosawa, Yoshikazu, Shirouzu, Mikako
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819829/
https://ncbi.nlm.nih.gov/pubmed/29462206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193158
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