STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation

The adaptor proteins STAC1, STAC2, and STAC3 represent a newly identified family of regulators of voltage-gated calcium channel (Ca(V)) trafficking and function. The skeletal muscle isoform STAC3 is essential for excitation–contraction coupling and its mutation causes severe muscle disease. Recently...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Campiglio, Marta, Costé de Bagneaux, Pierre, Ortner, Nadine J., Tuluc, Petronel, Van Petegem, Filip, Flucher, Bernhard E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819422/
https://ncbi.nlm.nih.gov/pubmed/29363593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715997115
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