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STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation
The adaptor proteins STAC1, STAC2, and STAC3 represent a newly identified family of regulators of voltage-gated calcium channel (Ca(V)) trafficking and function. The skeletal muscle isoform STAC3 is essential for excitation–contraction coupling and its mutation causes severe muscle disease. Recently...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5819422/ https://ncbi.nlm.nih.gov/pubmed/29363593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715997115 |
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