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Genomic screening for monogenic forms of diabetes
Adult-onset, or type II diabetes mellitus (T2DM) has a complex genetic architecture, from hundreds of genes with low penetrance, common susceptibility variants (e.g., TCF7L2), to a set of more than ten genes that, when mutated, can cause a single-gene or Mendelian form of T2DM (e.g., GCK). It is a c...
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| Veröffentlicht in: | BMC Med |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5819280/ https://ncbi.nlm.nih.gov/pubmed/29458357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1012-z |
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