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The EGFR-ADAM17 Axis in Chronic Obstructive Pulmonary Disease and Cystic Fibrosis Lung Pathology

Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) share molecular mechanisms that cause the pathological symptoms they have in common. Here, we review evidence suggesting that hyperactivity of the EGFR/ADAM17 axis plays a role in the development of chronic lung disease in both CF...

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Vydáno v:Mediators Inflamm
Hlavní autoři: Stolarczyk, Marta, Scholte, Bob J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818912/
https://ncbi.nlm.nih.gov/pubmed/29540993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1067134
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