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The EGFR-ADAM17 Axis in Chronic Obstructive Pulmonary Disease and Cystic Fibrosis Lung Pathology

Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) share molecular mechanisms that cause the pathological symptoms they have in common. Here, we review evidence suggesting that hyperactivity of the EGFR/ADAM17 axis plays a role in the development of chronic lung disease in both CF...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Stolarczyk, Marta, Scholte, Bob J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818912/
https://ncbi.nlm.nih.gov/pubmed/29540993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1067134
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