Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver

Many frequently prescribed drugs are non-genotoxic carcinogens (NGC) in rodent liver. Their mode of action and health risks for humans remain to be elucidated. Here, we investigated the impact of two model NGC, the anti-epileptic drug phenobarbital (PB) and the contraceptive cyproterone acetate (CPA...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Nejabat, Marzieh, Riegler, Teresa, Reitinger, Tabea, Subosits, Sandra, Römer, Michael, Eichner, Johannes, Bilban, Martin, Zell, Andreas, Huber, Wolfgang W., Schulte-Hermann, Rolf, Grasl-Kraupp, Bettina
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Genotoxicity and Carcinogenicity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818586/
https://ncbi.nlm.nih.gov/pubmed/29270806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2080-0
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