Diffusion Basis Spectrum and Diffusion Tensor Imaging Detect Hippocampal Inflammation and Dendritic Injury in a Virus-Induced Mouse Model of Epilepsy

Hippocampal CA1 inflammation and dendritic loss are common in epilepsy. Quantitative detection of coexisting brain inflammation and injury could be beneficial in monitoring disease progression and assessing therapeutic efficacy. In this work, we used conventional diffusion tensor imaging (DTI, known...

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Veröffentlicht in:Front Neurosci
Hauptverfasser: Zhan, Jie, Lin, Tsen-Hsuan, Libbey, Jane E., Sun, Peng, Ye, Zezhong, Song, Chunyu, Wallendorf, Michael, Gong, Honghan, Fujinami, Robert S., Song, Sheng-Kwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818459/
https://ncbi.nlm.nih.gov/pubmed/29497358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00077
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