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The radical SAM protein HemW is a heme chaperone

Radical S-adenosylmethionine (SAM) enzymes exist in organisms from all kingdoms of life, and all of these proteins generate an adenosyl radical via the homolytic cleavage of the S–C(5′) bond of SAM. Of particular interest are radical SAM enzymes, such as heme chaperones, that insert heme into respir...

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Pubblicato in:J Biol Chem
Autori principali: Haskamp, Vera, Karrie, Simone, Mingers, Toni, Barthels, Stefan, Alberge, François, Magalon, Axel, Müller, Katrin, Bill, Eckhard, Lubitz, Wolfgang, Kleeberg, Kirstin, Schweyen, Peter, Bröring, Martin, Jahn, Martina, Jahn, Dieter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818191/
https://ncbi.nlm.nih.gov/pubmed/29282292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000229
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