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NudE regulates dynein at kinetochores but is dispensable for other dynein functions in the C. elegans early embryo

In mitosis, the molecular motor dynein is recruited to kinetochores by the Rod–Zw10–Zwilch complex (RZZ) and Spindly to control spindle assembly checkpoint (SAC) signaling and microtubule attachment. How the ubiquitous dynein co-factors Lis1 and NudE contribute to these functions remains poorly unde...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Simões, Patrícia A., Celestino, Ricardo, Carvalho, Ana X., Gassmann, Reto
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818066/
https://ncbi.nlm.nih.gov/pubmed/29192061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.212159
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