The developmental and genetic basis of ‘clubfoot’ in the peroneal muscular atrophy mutant mouse

Genetic factors underlying the human limb abnormality congenital talipes equinovarus (‘clubfoot’) remain incompletely understood. The spontaneous autosomal recessive mouse ‘peroneal muscular atrophy’ mutant (PMA) is a faithful morphological model of human clubfoot. In PMA mice, the dorsal (peroneal)...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Collinson, J. Martin, Lindström, Nils O., Neves, Carlos, Wallace, Karen, Meharg, Caroline, Charles, Rebecca H., Ross, Zoe K., Fraser, Amy M., Mbogo, Ivan, Oras, Kadri, Nakamoto, Masaru, Barker, Simon, Duce, Suzanne, Miedzybrodzka, Zosia, Vargesson, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818009/
https://ncbi.nlm.nih.gov/pubmed/29439133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.160093
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