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Variant cell cycles regulated by Notch signaling control cell size and ensure a functional blood-brain barrier

Regulation of cell size is crucial in development. In plants and animals two cell cycle variants are employed to generate large cells by increased ploidy: the endocycle and endomitosis. The rationale behind the choice of which of these cycles is implemented is unknown. We show that in the Drosophila...

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Publicado en:Development
Autores principales: Von Stetina, Jessica R., Frawley, Laura E., Unhavaithaya, Yingdee, Orr-Weaver, Terry L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818001/
https://ncbi.nlm.nih.gov/pubmed/29440220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.157115
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