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The role of RICTOR downstream of receptor tyrosine kinase in cancers

The importance of the network defined by phosphatidylinositol-3-kinase (PI3K), AKT and mammalian target of rapamycin (mTOR) downstream of Receptor Tyrosine Kinase (RTK) has been known for many years but the central role of RICTOR (rapamycin-insensitive companion of mTOR) in this pathway is only star...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Jebali, Ahlem, Dumaz, Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817857/
https://ncbi.nlm.nih.gov/pubmed/29455662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0794-0
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