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Kinase-targeted cancer therapies: progress, challenges and future directions
The human genome encodes 538 protein kinases that transfer a γ-phosphate group from ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with human cancer initiation and progression. The recent development of small-molecule kinase inhibitors for the treatment of diver...
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| Publicado no: | Mol Cancer |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817855/ https://ncbi.nlm.nih.gov/pubmed/29455673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0804-2 |
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