Third generation EGFR TKIs: current data and future directions

Acquired T790 M mutation is the commonest cause of resistance for advanced non-small cell lung cancer (NSCLC) epidermal growth factor receptor (EGFR) mutant patients who had progressed after first line EGFR TKI (tyrosine kinase inhibitor). Several third generation EGFR TKIs which are EGFR mutant sel...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Tan, Chee-Seng, Kumarakulasinghe, Nesaretnam Barr, Huang, Yi-Qing, Ang, Yvonne Li En, Choo, Joan Rou-En, Goh, Boon-Cher, Soo, Ross A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817792/
https://ncbi.nlm.nih.gov/pubmed/29455654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0778-0
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