Third generation EGFR TKIs: current data and future directions

Acquired T790 M mutation is the commonest cause of resistance for advanced non-small cell lung cancer (NSCLC) epidermal growth factor receptor (EGFR) mutant patients who had progressed after first line EGFR TKI (tyrosine kinase inhibitor). Several third generation EGFR TKIs which are EGFR mutant sel...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer
Autori principali: Tan, Chee-Seng, Kumarakulasinghe, Nesaretnam Barr, Huang, Yi-Qing, Ang, Yvonne Li En, Choo, Joan Rou-En, Goh, Boon-Cher, Soo, Ross A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817792/
https://ncbi.nlm.nih.gov/pubmed/29455654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0778-0
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