Melatonin Modulation of Sirtuin-1 Attenuates Liver Injury in a Hypercholesterolemic Mouse Model

Hypercholesterolemia increases and exacerbates stress signals leading also to liver damage (LD) and failure. Sirtuin1 (SIRT1) is involved in lifespan extension and it plays an essential role in hepatic lipid metabolism. However, its involvement in liver hypercholesterolemic damage is not yet complet...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Bonomini, Francesca, Favero, Gaia, Rodella, Luigi Fabrizio, Moghadasian, Mohammed H., Rezzani, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817311/
https://ncbi.nlm.nih.gov/pubmed/29516009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7968452
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