Effects of Long‐Term Alcohol Drinking on the Dopamine D2 Receptor: Gene Expression and Heteroreceptor Complexes in the Striatum in Rats

BACKGROUND: Reduced dopamine D2 receptor (D2R) ligand binding has repeatedly been demonstrated in the striatum of humans with alcohol use disorder (AUD). The attenuated D2R binding has been suggested to reflect a reduced D2R density, which in turn has been proposed to drive craving and relapse. Howe...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Feltmann, Kristin, Borroto‐Escuela, Dasiel Oscar, Rüegg, Joëlle, Pinton, Luca, de Oliveira Sergio, Thatiane, Narváez, Manuel, Jimenez‐Beristain, Antonio, Ekström, Tomas J., Fuxe, Kjell, Steensland, Pia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817245/
https://ncbi.nlm.nih.gov/pubmed/29205397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13568
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