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Design of a humanized anti vascular endothelial growth factor nanobody and evaluation of its in vitro function

OBJECTIVE(S): Nanobodies, the single domain antigen binding fragments of heavy chain-only antibodies occurring naturally in camelid sera, are the smallest intact antigen binding entities. Their minimal size assists in reaching otherwise largely inaccessible regions of antigens. However, their cameli...

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Détails bibliographiques
Publié dans:Iran J Basic Med Sci
Auteurs principaux: Kazemi-Lomedasht, Fatemeh, Muyldermans, Serge, Habibi-Anbouhi, Mahdi, Behdani, Mahdi
Format: Artigo
Langue:Inglês
Publié: Mashhad University of Medical Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817169/
https://ncbi.nlm.nih.gov/pubmed/29511492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2018.24898.6183
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