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Potentiation of the activity of β-lactam antibiotics by farnesol and its derivatives
Farnesol, a sesquiterpene alcohol, potentiates the activity of β-lactam antibiotics against antibiotic-resistant bacteria. We document that farnesol and two synthetic derivatives (compounds 2 and 6) have poor antibacterial activities of their own, but they potentiate the activities of ampicillin and...
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| Publicado en: | Bioorg Med Chem Lett |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817034/ https://ncbi.nlm.nih.gov/pubmed/29402738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.01.028 |
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