(212)Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models

INTRODUCTION: We recently validated monoclonal antibody (mAb) 376.96 as an effective carrier for targeted α-particle radioimmunotherapy (RIT) with (212)Pb in ovarian cancer mouse models. In this study, we tested the binding of radiolabeled mAb 376.96 to human pancreatic ductal adenocarcinoma (PDAC)...

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Detalhes bibliográficos
Publicado no:Nucl Med Biol
Main Authors: Kasten, Benjamin B., Gangrade, Abhishek, Kim, Harrison, Fan, Jinda, Ferrone, Soldano, Ferrone, Cristina R., Zinn, Kurt R., Buchsbaum, Donald J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817013/
https://ncbi.nlm.nih.gov/pubmed/29413459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2017.12.004
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