Scutellarin Increases Cisplatin-Induced Apoptosis and Autophagy to Overcome Cisplatin Resistance in Non-small Cell Lung Cancer via ERK/p53 and c-met/AKT Signaling Pathways

Cisplatin, as the first-line anti-tumor agent, is widely used for treatment of a variety of malignancies including non-small cell lung cancer (NSCLC). However, the acquired resistance has been a major obstacle for the clinical application. Scutellarin is a active flavone extracted from Erigeron brev...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Sun, Chao-Yue, Zhu, Ying, Li, Xiao-Feng, Wang, Xie-Qi, Tang, Li-Peng, Su, Zu-Qing, Li, Cai-Yun, Zheng, Guang-Juan, Feng, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816782/
https://ncbi.nlm.nih.gov/pubmed/29487530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00092
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