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Critical issues and optimized practices in quantification of protein abundance level to determine inter-individual variability in DMET proteins by LC-MS/MS proteomics

Protein quantification data on drug metabolizing enzymes and transporters (collectively referred as DMET proteins) in human tissues are useful in predicting interindividual variability in drug disposition. While targeted proteomics is an emerging technique for quantification of DMET proteins, the me...

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Bibliografische gegevens
Gepubliceerd in:Clin Pharmacol Ther
Hoofdauteurs: Bhatt, Deepak Kumar, Prasad, Bhagwat
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816727/
https://ncbi.nlm.nih.gov/pubmed/28833066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.819
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