Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype

BACKGROUND: During embryonic development Wnt family members and bone morphogenetic proteins (BMPs) cooperatively induce epithelial-mesenchymal transition (EMT) in the neural crest. Wnt and BMPs are reactivated during malignant transformation in melanoma. We previously demonstrated that the BMP-antag...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer
Egile Nagusiak: Sinnberg, Tobias, Levesque, Mitchell P., Krochmann, Jelena, Cheng, Phil F., Ikenberg, Kristian, Meraz-Torres, Francisco, Niessner, Heike, Garbe, Claus, Busch, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816360/
https://ncbi.nlm.nih.gov/pubmed/29454361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0773-5
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